Top 200 Drugs for 2007 by Sales
Drugstores Online
Rank Product US Sales (U.S.$ Billions) % change from 2006
1 Lipitor 6.165 -6.3
2 Nexium 4.355 7.3
3 Advair Diskus 3.390 8.8
4 Prevacid 3.315 0.3
5 Plavix 3.082 38.1
6 Singulair 2.863 16.4
7 Seroquel 2.518 21.4
8 Effexor XR 2.464 9.7
9 Lexapro 2.304 9.8
10 Actos 2.229 15.7
11 Protonix 2.136 5.7
12 Vytorin 1.938 32
13 Topamax 1.837 20.8
14 Risperdal 1.790 8.1
15 Abilify 1.781 25.7
16 Cymbalta 1.732 59.8
17 Lamictal 1.717 29.4
18 Zyprexa 1.579 2.8
19 Levaquin 1.433 1.7
20 Celebrex 1.416 7.6
21 Zetia 1.405 23.3
22 Valtrex 1.395 21.3
23 Crestor 1.367 29.2
24 Fosamax 1.355 -5
25 Zyrtec 1.302 12
26 Lantus 1.302 23.1
27 Adderall XR 1.288 13.9
28 Diovan 1.117 15
29 Avandia 1.110 -33.3
30 Tricor 1.106 14.6
31 Aciphex 1.099 -1.2
32 Diovan HCT 1.051 21.4
33 OxyContin 1.043 52.8
34 Concerta 1.030 10.1
35 Coreg 1.013 -12.5
36 Flomax 1.002 27.6
37 Lyrica 1.000 53.6
38 Wellbutrin XL .992 -40.6
39 Aricept .983 22.9
40 Imitrex Oral .950 10.8
41 Ambien .920 -52.5
42 Lotrel .908 -29.8
43 Nasonex .892 13.1
44 Toprol XL .888 -39.7
45 Ambien CR .876 58.4
46 Enbrel .874 -19.3
47 Spiriva .868 46.3
48 Viagra .824 4.9
49 Lidoderm .808 27.1
50 Actonel .791 1.3
51 Chantix .764 777.5
52 Norvasc .749 -65.1
53 Lovenox .746 25.1
54 Provigil .744 15.5
55 Lunesta .712 22.1
56 Altace .710 -1
57 Keppra .708 42
58 Geodon Oral .665 25.6
59 Cozaar .652 5.4
60 Detrol LA .635 8.8
61 Atripla .617 471
62 Truvada .606 6.4
63 CellCept .599 18.1
64 Pulmicort Respules .592 13.8
65 Humalog .592 11
66 Depakote ER .577 15
67 Depakote .573 5.9
68 Premarin Tabs .557 -3.3
69 Synthroid .547 -5.5
70 Niaspan .546 15.3
71 Byetta .541 49
72 Budeprion XL .537 >999
73 Strattera .535 -7.3
74 Combivent .534 -0.1
75 Trileptal .532 3.7
76 Yasmin 28 .528 4
77 Flovent HFA .521 9.3
78 Skelaxin .517 7.1
79 Prograf .515 15.7
80 Arimidex .506 13.5
81 Evista .503 -0.9
82 Hyzaar .499 5.3
83 Namenda .489 26.6
84 Januvia .471 >999
85 Humira .462 -8.5
86 Cialis .453 20.8
87 Reyataz .438 17.7
88 Xalatan .430 6.7
89 Omnicef .429 -44.5
90 Avelox .424 26.5
91 ProAir HFA .421 678.6
92 Asacol .420 8.4
93 Benicar HCT .414 24.1
94 Fentanyl Oral Citra .408 515.9
95 Requip .407 56.3
96 Boniva .404 49.5
97 Caduet .388 0.2
98 Avapro .384 0.2
99 Gleevec .384 13.7
100 Kaletra .373 6
101 Ortho Tri-Cyclen Lo .371 -0.1
102 Benicar .369 18.2
103 AndroGel .366 23.8
104 Xopenex .354 10.8
105 Procrit .353 -15.6
106 Lamisil Oral .339 -44.6
107 Avalide .328 9.3
108 Nasacort AQ .318 6.3
109 Combivir .318 -10.6
110 Allegra-D 12 Hour .316 -5.5
111 Duragesic .306 -14.3
112 Copaxone .303 -0.7
113 RenaGel .293 29.8
114 Femara .293 23.6
115 Enbrel Sureclick .293 539.1
116 NovoLog Mix 70/30 .292 22.8
117 Clarinex .288 -8.6
118 Aldara .287 18.4
119 Forteo .282 -4.3
120 Suboxone .282 105.9
121 Avodart .281 45.9
122 Paxil CR .280 -14.2
123 Norvir .275 10.3
124 Avandamet .275 101.6
125 Restasis .274 31.7
126 Avonex .266 -7.7
127 Sensipar .266 49.8
128 Tarceva .263 7.5
129 Patanol .258 -11.1
130 Yaz .254 584
131 Lovaza .252 121.5
132 Mirapex .249 26.5
133 Focalin XR .249 56.6
134 Cosopt .242 8.5
135 Zyvox .236 15.5
136 Epzicom .230 27.2
137 NuvaRing .230 33.2
138 Actiq .230 -57.9
139 Fosamax Plus D .229 69.1
140 Actoplus Met .229 94.9
141 Lumigan .226 11.4
142 Rhinocort Aqua .225 -11.4
143 Solodyn .224 247.7
144 Thalomid .222 -18.6
145 Fuzeon .220 -13.9
146 Astelin .219 17.3
147 BenzaClin .213 5
148 Relpax .212 3.9
149 Viread .210 -5.8
150 Casodex .207 7.7
151 Vigamox .207 12.2
152 Vesicare .205 77.6
153 Humalog Mix 75/25 Pn .204 2
154 Trizivir .203 -8.7
155 Budeprion SR .201 -4.6
156 Xeloda .201 12.2
157 Sustiva .200 -33.5
158 Levitra .197 11.4
159 Endocet .193 -14.5
160 Risperdal Consta .193 36.1
161 Aggrenox .193 27.1
162 Humira Pen .191 741.1
163 Kadian .191 23.6
164 Differin .188 11.4
165 Catapres-TTS .187 7.6
166 Alphagan P .186 9.7
167 Tussionex .179 -0.1
168 Zyrtec Syrup .177 3.7
169 Maxalt .176 22.4
170 Zoloft .175 -90.1
171 Prilosec .174 -0.2
172 Ciprodex Otic .174 10.6
173 Temodar .173 -2.1
174 Tobradex .172 3.7
175 Zyrtec-D .163 -2.6
176 Welchol .161 23.8
177 Maxalt MLT .161 15.5
178 Asmanex .161 75
179 Atacand .160 2.6
180 Coumadin Tabs .160 -10.2
181 Dovonex .159 11.1
182 Klor-Con .159 -2.4
183 Pegasys .156 0.7
184 Ultram ER .155 117
185 Betaseron .151 -3.8
186 Zovirax Topical .151 18.8
187 Trinessa .151 -3.6
188 Pulmozyme .150 3.7
189 Neupogen .150 -5.8
190 Humulin N .149 -8.2
191 Micardis HCT .148 34
192 Ortho Evra .148 -36.4
193 Allegra-D 24 Hour .148 34.2
194 Fentora .147 762.8
195 Enablex .147 61.5
196 Famvir .146 -8.6
197 Avinza .145 -2.5
198 Prempro .144 4.4
199 Coreg CR .144 NA
200 Marinol .144 14.3
All Others 25.961 -11.7
Source: Verispan, VONA
Saturday, December 27, 2008
The Best-Selling Drugs In America
Pharmaceuticals
The Best-Selling Drugs In America
Matthew Herper, 02.27.06
Drugstores Online
NEW YORK -- Lipitor, the cholesterol-lowering treatment, remains the best-selling drug in America. But Pfizer, the drug's maker, is facing renewed competition from biotechs like Amgen that were hardly on the map a decade ago-- and renewed threats from cheap generic drugs.
That's the picture from newly released data from IMS Health, a pharmaceutical information and consulting company that independently keeps track of how often medicines are prescribed and how much revenue they are generating. IMS has provided to Forbes a list of the top 20 medicines by U.S. sales (See: "America's 20 Best-Selling Drugs") and an exclusive look at the medicines whose U.S. sales are increasing at the fastest clip (See: "America's Fastest Growing Medicines.")
Click here for America's 20 Best-Selling Drugs
The drug industry is undergoing a major shift, as players like Pfizer and Merck that have been around for a hundred years are giving ground to biotech players like Amgen and Genentech that weren't around 30 years ago. Overall, drug sales grew 5.4% to $252 billion in 2005. But sales of biotech drugs like Amgen's Aranesp and Genentech's Rituxan grew 17% to $33 billion. These are often very expensive, injectable medicines used for hard-to-treat diseases like cancer, severe anemia and rheumatoid arthritis.
According to IMS Health's data, Pfizer makes three of the top 20 drugs in the U.S. Amgen makes four of them, including Aranesp, Epogen, Neulasta and Enbrel. What's more, Pfizer's Zoloft, for depression, and Norvasc, for high blood pressure, lose patent protection this year and next, respectively, potentially leaving Lipitor as the world's largest drug company's only entrant in the top 20. Generic drugs, cheap knockoffs that hit the market after medicines lose patent protection, saw sales jump 20%. That is only going to get worse as Zocor, Merck's cholesterol treatment, loses patent protection this summer. A new Medicare drug benefit may increase the number of patients popping pills, but also push more of them toward the cheap generics.
Another problem for old line drug firms: fewer new medicines are being approved, with 20 new drugs approved by U.S. regulators in 2005 compared with 53 in 1996. "You have success rates that haven't improved in 30 years," says Amgen research chief Roger Perlmutter, a former Merck researcher, in the current issue of Forbes (see: "Storm Warnings").
Click here for America's Fastest-Growing Medicines
The biggest sellers are treatments for high cholesterol, like Lipitor and Zocor, bringing in $16 billion in 2005 U.S. sales, according to IMS. Vytorin, a new medicine for cholesterol from Merck and Schering-Plough, saw the biggest share gains on the list of fast-growing medicines. (It benefits some by only having been on sale for half of 2004.) Medicines like Nexium, the AstraZeneca pill for heartburn, are big sellers as well. These types of heartburn drugs brought in $13 billion in the U.S.
Schizophrenia medicines are another big ($11 billion) and hotly contested area. These drugs are increasingly used for bipolar disease and also for other mental illnesses, including some for which they have not been approved by the Food and Drug Administration. A major shift: Seroquel, from AstraZeneca, has passed Zyprexa from Eli Lilly and Risperdal form Johnson & Johnson as the top-selling schizophrenia drug. One possible reason: controversy over Zyprexa's potential to cause weight gain in some patients. Abilify, a schizophrenia medicine from Bristol-Myers Squibb and Japan's Otsuka, is also gaining ground fast.
Still, many of the biggest winners are biotech drugs. Genentech's Avastin, for colorectal cancer, saw sales increase 247% to $948 million in 2005, and its Herceptin for breast cancers saw a jump of 52% to $750 million. As reported in the current issue of Forbes, some analysts forecast that by 2010, Amgen will be as big as Merck, once the largest U.S. drug maker.
The Best-Selling Drugs In America
Matthew Herper, 02.27.06
Drugstores Online
NEW YORK -- Lipitor, the cholesterol-lowering treatment, remains the best-selling drug in America. But Pfizer, the drug's maker, is facing renewed competition from biotechs like Amgen that were hardly on the map a decade ago-- and renewed threats from cheap generic drugs.
That's the picture from newly released data from IMS Health, a pharmaceutical information and consulting company that independently keeps track of how often medicines are prescribed and how much revenue they are generating. IMS has provided to Forbes a list of the top 20 medicines by U.S. sales (See: "America's 20 Best-Selling Drugs") and an exclusive look at the medicines whose U.S. sales are increasing at the fastest clip (See: "America's Fastest Growing Medicines.")
Click here for America's 20 Best-Selling Drugs
The drug industry is undergoing a major shift, as players like Pfizer and Merck that have been around for a hundred years are giving ground to biotech players like Amgen and Genentech that weren't around 30 years ago. Overall, drug sales grew 5.4% to $252 billion in 2005. But sales of biotech drugs like Amgen's Aranesp and Genentech's Rituxan grew 17% to $33 billion. These are often very expensive, injectable medicines used for hard-to-treat diseases like cancer, severe anemia and rheumatoid arthritis.
According to IMS Health's data, Pfizer makes three of the top 20 drugs in the U.S. Amgen makes four of them, including Aranesp, Epogen, Neulasta and Enbrel. What's more, Pfizer's Zoloft, for depression, and Norvasc, for high blood pressure, lose patent protection this year and next, respectively, potentially leaving Lipitor as the world's largest drug company's only entrant in the top 20. Generic drugs, cheap knockoffs that hit the market after medicines lose patent protection, saw sales jump 20%. That is only going to get worse as Zocor, Merck's cholesterol treatment, loses patent protection this summer. A new Medicare drug benefit may increase the number of patients popping pills, but also push more of them toward the cheap generics.
Another problem for old line drug firms: fewer new medicines are being approved, with 20 new drugs approved by U.S. regulators in 2005 compared with 53 in 1996. "You have success rates that haven't improved in 30 years," says Amgen research chief Roger Perlmutter, a former Merck researcher, in the current issue of Forbes (see: "Storm Warnings").
Click here for America's Fastest-Growing Medicines
The biggest sellers are treatments for high cholesterol, like Lipitor and Zocor, bringing in $16 billion in 2005 U.S. sales, according to IMS. Vytorin, a new medicine for cholesterol from Merck and Schering-Plough, saw the biggest share gains on the list of fast-growing medicines. (It benefits some by only having been on sale for half of 2004.) Medicines like Nexium, the AstraZeneca pill for heartburn, are big sellers as well. These types of heartburn drugs brought in $13 billion in the U.S.
Schizophrenia medicines are another big ($11 billion) and hotly contested area. These drugs are increasingly used for bipolar disease and also for other mental illnesses, including some for which they have not been approved by the Food and Drug Administration. A major shift: Seroquel, from AstraZeneca, has passed Zyprexa from Eli Lilly and Risperdal form Johnson & Johnson as the top-selling schizophrenia drug. One possible reason: controversy over Zyprexa's potential to cause weight gain in some patients. Abilify, a schizophrenia medicine from Bristol-Myers Squibb and Japan's Otsuka, is also gaining ground fast.
Still, many of the biggest winners are biotech drugs. Genentech's Avastin, for colorectal cancer, saw sales increase 247% to $948 million in 2005, and its Herceptin for breast cancers saw a jump of 52% to $750 million. As reported in the current issue of Forbes, some analysts forecast that by 2010, Amgen will be as big as Merck, once the largest U.S. drug maker.
Top 10 Drugs By Sales - 2006
Top 10 Drugs By Sales - 2006
US Sales in $Billions
The following are the top 10 selling drugs in the USA for the year 2006.
Drugstores Online
#1 - Lipitor
$6.58 Billion. Lipitor is a cholesterol-lowering medication that blocks the production of cholesterol.
#2 - Nexium
$4.06 Billion. Nexium decreases the amount of acid produced in the stomach.
#3 - Prevacid
$3.31 Billion. Prevacid also decreases the amount of acid produced in the stomach.
#4 - Advair Diskus
$3.11 Billion. Advair is used to prevent asthma attacks.
#5 - Singulair
$2.46 Billion. Singulair is used to prevent asthma attacks in adults and children.
#6 - Effexor XR
$2.25 Billion. Effexor is used to treat major depressive disorders, anxiety, and panic disorders.
#7 - Plavix
$2.23 Billion. Plavix is used to prevent blood clots after a recent heart attack or stroke.
#8 - Zocor
$2.17 Billion. Zocor is als a cholesterol-lowering medication that blocks the production of cholesterol.
#9 - Norvasc
$2.15 Billion. Norvasc is used to treat hypertension (high blood pressure) and to treat angina (chest pain).
#10 - Lexapro
$2.10 Billion. Lexapro is an antidepressant. Lexapro is used to treat anxiety and major depressive disorder.
Top Drugs for 2005
1 Lipitor
2 Nexium
3 Zocor
4 Zocor
5 Advair Diskus
6 Zoloft
7 Plavix
8 Effexor XR
9 Singulair
10 Norvasc
Top Drugs for 2004
1 Lipitor
2 Zocor
3 Prevacid
4 Nexium
5 Procrit
6 Zoloft
7 Plavix
8 Advair Diskus
9 Zyprexa
10 Celebrex
Top Drugs for 2003
1 Lipitor
2 Zocor
3 Prevacid
4 Procrit
5 Nexium
6 Zyprexa
7 Zoloft
8 Celebrex
9 Epogen
10 Neurontin
Largest Lottery Payouts Ever
Largest Lottery Payouts Ever
These are the largest payoffs in American lottery history:
1. $365 million - Powerball - On February 18, 2006, the jackpot worth $365 million was won by a single ticket sold in
Lincoln, Nebraska. That single ticket was shared by eight meat plant workers. This is the largest Powerball prize (per ticket).
2. $340 million - Powerball - A grand prize won on October 19, 2005 worth $340 million was awarded to the West family in
Jacksonville, Oregon. The family won less than two months after the rules were changed to promote larger payouts. Steve West, who purchased the ticket, put in $20 for tickets, along with another $20 from his in-laws. The family planned to split the prize among themselves.
3. $314 million - Powerball - Jack Whittaker of West Virginia was the claimant to the biggest jackpot. He won $314 million on Christmas Day, 2002.
4. $314 million - Powerball - On August 25, 2007, a jackpot worth $314 million was won by a retired auto worker from Ohio.
5. $390M - Mega Millions - On March 6, 2007, two ticket holders won the world's largest jackpot
6. $363M - Mega Millions - On May 9, 2000, two ticket holders won the largest Big Game prize
7. $330M - Mega Millions - On August 31, 2007, four ticket holders won the largest shared MM prize
8. $315M - Mega Millions - On November 15, 2005, a single person won the largest single winning ticket prize
These are the largest payoffs in American lottery history:
1. $365 million - Powerball - On February 18, 2006, the jackpot worth $365 million was won by a single ticket sold in
Lincoln, Nebraska. That single ticket was shared by eight meat plant workers. This is the largest Powerball prize (per ticket).
2. $340 million - Powerball - A grand prize won on October 19, 2005 worth $340 million was awarded to the West family in
Jacksonville, Oregon. The family won less than two months after the rules were changed to promote larger payouts. Steve West, who purchased the ticket, put in $20 for tickets, along with another $20 from his in-laws. The family planned to split the prize among themselves.
3. $314 million - Powerball - Jack Whittaker of West Virginia was the claimant to the biggest jackpot. He won $314 million on Christmas Day, 2002.
4. $314 million - Powerball - On August 25, 2007, a jackpot worth $314 million was won by a retired auto worker from Ohio.
5. $390M - Mega Millions - On March 6, 2007, two ticket holders won the world's largest jackpot
6. $363M - Mega Millions - On May 9, 2000, two ticket holders won the largest Big Game prize
7. $330M - Mega Millions - On August 31, 2007, four ticket holders won the largest shared MM prize
8. $315M - Mega Millions - On November 15, 2005, a single person won the largest single winning ticket prize
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